Background The hepatocellular carcinoma (HCC) immune microenvironment is heavily influenced by immunosuppressive neutrophils, yet the mechanisms driving their senescence-associated reprogramming remain elusive. Objectives To elucidate the r…
Objectives Patient decision aids (PtDAs) are effective interventions to support patient involvement in health decisions and have the potential to impact favourably on health inequities by reducing gender bias in clinical practice. The aim w…
Just a few weeks apart, parliaments in Scotland and Jersey voted on assisted dying legislation with very different outcomes. The Assisted Dying for Terminally Ill Adults Bill was rejected in Scotland, while a draft law on assisted dying was…
Mental health drug purchases lower among those with more siblings after mother’s death Having more brothers and sisters may make it easier to cope with the death of a parent, in midlife, particularly when it’s the mother who dies, suggests
May confer immediate to short term benefits, but current evidence “very uncertain” This, plus potential skin irritation, may limit its use in clinical practice, conclude researchers Kinesio taping, or ‘KT tape’ as it’s usually known—widely
Introduction Current international guidelines recommend exercise as a first-line treatment of axial spondyloarthritis (SpA). However, there is no consensus on the mode and volume required to effectively reduce disease activity. It is advise…
Background Survival outcomes after transarterial chemoembolisation (TACE) vary in hepatocellular carcinoma (HCC) patients, and existing prognostic scores and imaging models often lack generalisability and biological interpretability. Object…
Reforms to the General Medical Council will not allow physician assistants (PAs) to receive certificates of completion of training (CCTs), the government and regulator have said.Doctors raised the matter after the Department of Health and S…
Objective There is limited evidence on the association between lifestyle factors and breast cancer (BC) incidence from Australian longitudinal studies. This study aims to investigate the influence of lifestyle factors on BC incidence over t…
HallucinationsThe word “hallucination” comes from the past participle of the Latin verb alucinari, to wander in one’s mind, to talk idly, or to prattle. The verb to hallucinate first appeared in written English in the first monolingual Engl…
Elevated troponin I (TnI) has been reported in patients with chronic obstructive pulmonary disease (COPD) without cardiovascular disease (CVD), suggesting non-ischaemic mechanisms. We assessed this association in a population-based cohort o…
Clinical presentation A 70-year-old woman with no significant comorbidities presented to the emergency department with a 3-day history of asthenia, mild abdominal pain and melena. She reported recent non-steroidal anti-inflammatory drug use…