The purpose of this study is to find out if researchers can lower the chance of non-muscle invasive bladder cancer growing or spreading by using a combination of drugs called durvalumab and monalizumab. This combination of drugs has been te…
The purpose of this study is to evaluate the safety and efficacy of IDE849 in participants with extensive stage small cell lung cancer (ES-SCLC), neuroendocrine carcinoma (NEC), and other delta-like protein 3 (DLL3)-expressing solid tumors.…
This study is for female and male patients who are 18 years of age and older, have a body mass index of 30-50 kg/m2 and have had difficulties losing weight or maintaining weight loss despite prior attempts with non-surgical weight-loss meth…
The purpose of this study to is to assess the feasibility and acceptability of using a point-of-care (POC) prostate specific antigen (PSA) test to screen men for prostate cancer in a community setting.In this study, participants will receiv…
The purpose of this study is to evaluate the safety and effectiveness of bright light therapy for patients with melanoma and non-small cell lung cancer (NSCLC).In this study, bright light therapy will be provided via an iPad at the particip…
This clinical trial is for adults who have relapsed/refractory acute lymphoblastic leukemia (ALL) and the Obe-Cel product prescribed by their study doctor did not meet commercial release criteria.The purpose of this Out-Of-Specification (OO…
This clinical trial is for adults who have blood cancer or precancerous conditions that are highly likely to turn into blood cancer.The purpose of this study is to answer the following primary questions:Can the investigational drug Orca-T b…
The purpose of this study is to compare the effectiveness of 6 months of HER2-targeted medications (trastuzumab with or without pertuzumab) versus 12 months of HER2-targeted medications at reducing the risk of breast cancer coming back or d…
The purpose of this pilot study is to evaluate a new decision support tool (“COAST”), designed for people with advanced breast cancer. This tool is intended to support patients and their providers to have meaningful conversations regarding
This study is being done to determine if the addition of a high dose of radiation therapy extends or improves quality of life in patients with locally advanced pancreatic cancer. Locally advanced means that the cancer cannot be removed by s…
This is a prospective observational study of clinical and patient-provided outcomes for individuals with sex chromosome aneuploidy (SCA) conditions throughout the lifespan: the GALAXY Registry. The overarching aim of the GALAXY Registry is
This post market surveillance study is a single arm multicenter study to demonstrate the long-term durability and effectiveness of the BioHealx Anal Fistula Device for fistula-in-ano closure (internal and external fistula openings). The Bio…