New mechanism in BRCA2 tumors discovered: why chemotherapy sometimes fails - Amazing Erasmus MC

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Some BRCA2 tumors can still repair their DNA damage: This means that even with chemotherapy, these tumors might not be fully eradicated.
Tumors use an alternate DNA repair mechanism to survive: Understanding this allows for the development of more targeted therapies that could overcome resistance. Fique de olho
Development of new drugs targeting alternative DNA repair mechanisms in BRCA2 tumors.

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New mechanism in BRCA2 tumors discovered: why chemotherapy sometimes fails - Amazing Erasmus MC

Why do some BRCA2 tumors eventually stop responding to chemotherapy? Researchers at Erasmus MC discovered how these tumors are still able to repair their DNA damage and how they evade the effects of chemotherapy.

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